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Weight Loss (Triumph-4)

Treatment for participants with Osteoarthritis of the Knee (Triumph-4)

Study Title

A Phase 3 Study to Investigate the Efficacy and Safety of LY3437943 Once Weekly in Participants who have Obesity or Overweight and Osteoarthritis of the Knee: A Randomized, Double-Blind, Placebo-Controlled Trial (TRIUMPH-4).

Purpose of Study

LY3437943 is a novel synthetic peptide which shows potent agonist activity at glucose dependent insulinotropic polypeptide, GLP-1, and glucagon receptors. LY3437943 demonstrated body weight reduction in preclinical models.  Data from clinical studies suggest that LY3437943 may represent a pharmacologic treatment option that could substantially reduce weight and thereby reduce knee OA pain in participants who have obesity or overweight.


You may be eligible for the study if you meet the following criteria.

For Osteoarthritis, you have at least 1 of the following.

Please contact CDH Research Institute on 07 5408 0900 for additional information or use the email link below. You can also share details of this study to social media via the links below?

CDH Research Institute

Complete the form to register.

CDH Research Institute

Complete the form to register.